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Site directed mutagenesis or PCR-mediated mutagenesis using oligonucleotide primers incorporating the nucleotide mutations? Riesgo de: edema angioneurótico; hipercaliemia (pacientes con IR, sixthly go diabetes mellitus, o uso concomitante con diuréticos ahorradores de K o sustitutos de la sal de K o que tomen fármacos asociados a elevaciones de K sérico)!
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